Research paper for crohns disease
The purpose of this study is to determine whether taking a growth remorse (GHZ) drug called comparison causes the intestine of a person with Crown’s Disease (CD) to heal faster when compared to a person with Crown’s Disease that does not receive growth hormone drug. C. The primary goal is to determine the effect of GHZ therapy upon colon mucosa healing in a 12 week randomized trial in children with CD. Children with active CD will be randomized to GHZ+ predations(GAP) or predations(P) alone for a 12 week period.
This study also involves a 52 week extension phase where all participants that meet eligibility will be given the opportunity to take or intuition taking growth hormone for 52 weeks. D. Lee Denton, M. D. Of the Children’s Hospital Medical Center in Cincinnati conducted the trial. E. The trail is being conducted at Cincinnati Children’s Hospital Medical Center. F. 22 children enrolled g. Qualifications include a written consent form, and being child aged 5 or under with moderate to severe CD. H. Trial started on April 28, 2005 and was last updated on October 10, 2011. I.
Results showed no new information 2. Mucosa Healing Study in Crown’s Disease #2 a. Completed b. Crematoriums Peggy in patients with CD is being tested. . The primary goal is to investigate the effect of crematoriums Peggy on the intestinal mucosa in active CD. D. Trial sponsored by JIB. E. No specific scientist was given credit for the trial. F. The trails were conducted in France, Belgium, and Germany. G. 89 people enrolled. H. Qualifications include having been over the age of 18 with moderate to severe CD and need to be treated by anti-tumor necrosis factor therapy. . Trial started in February of 2006, and ended on August 30, 2011. J. Results not explained in text. 3. Comparison of Standard and Low Dose CT Interrogatory for CD #3 a. Recruiting b. The scientists’ testing involves the collection of data from subjects standard of care diagnostic CT scan and from a research low radiation dose scan performed immediately following their diagnostic scan. C. The primary goal is to comparison the standard and low cosec CT Interrogatory in patients with CD. D. The trail sponsor is the University of British Columbia f.
The trials were conducted in the University of British Columbia. G. 166 people enrolled. H. Qualifications include being over 19 years of age and with suspected or known inflammatory bowel disease referred to the SST. Pall’s Hospital Radiology department for CT Interrogatory examination. I. Trail started on November 6, 2012 and is estimated to end on November 2014. 4. Evaluation Of Capsule Endoscope in patients With Suspected CD #4 a. Completed b. Being tested is Capsule Endoscope (CE) to accurately diagnose small bowel (SUB) CD in patients with symptoms of abdominal pain and diarrhea. C.
The primary objective is to evaluate whether Capsule Endoscope prior to oscilloscope will improve diagnosis in patients with suspected CD when compared to standard diagnostic testing. D. Sponsor is Given Imaging Ltd. . The trail is being conducted by Jonathan Leighton, MD. And Peter Elegant, MD. F. The trial is being conducted the US, Canada, Israel, and Sweden. G. 98 h. Qualifications include being between the ages of 10 and 65, and suffering from diarrhea and abdominal pains for more than 6 weeks, but less than 3 years. I. Trail began on June 14, 2007, and ended on April 1 7, 2012. J.
Results show that taking CE helped detect CD early in half the patients who participated. 5. Efficacy and Safety Study of 14TH-C 9 MGM and 15 MGM Versus Placebo in Japanese Patients With Active CD #5 a. Completed b. 14TH -C on Japanese patients with CD is being tested. C. The primary goal of the trial is to determine whether treatment with 14TH- C for 8 weeks in Japanese patients with mild to moderate active CD will improve their symptoms of CD and quality of life. D. Austereness is sponsoring the trial. E. Mistake Date, MD, PhD is conducting the trail. F. The trial is being conducted in Japan. G. 75 people enrolled. . Qualifications: Being male or female aged 18 to 65 with CD. I. Trial began on December 13, 2007, and ended on July 2, 201 2 j. Results show 6. Contrast Enhanced Ultrasonically (CUES) of patients With CD a. B. Being tested is to see if high frequency iconography and contrast enhanced iconography can be used to predict remission in patients with deterioration of CD treated with steroids or tumor necrosis factor (TNT) Alfa inhibitors. C. The primary goal is to see if high frequency sonograms can help with the remission of CD. D. Wasteland University Hospital and the University of Bergen sponsor the trail. . Trying Hauser, PhD is conducting the trial. F. The trial is being conducted in the Wasteland university Hospital. G. 30 estimated to be enrolled. H. Qualifications: Deterioration of CD, and recently treated with systemic terrorist or TNT Alfa inhibitors. I. Trials began on February 23, 201 0, and last updated on August 28, 2013. J. Results still pending. 7. A Crown’s Disease Diet to Reduce Symptoms of Crown’s Disease #7 a. B. Being tested is food that is gluten and casein-free with limited carbohydrate on people with mild to moderate CD to see if it reduces their symptoms. C.
The primary goal is to test different food groups to see if it reduces the symptoms Of people with CO. D. The trial is being sponsored by Johns Hopkins university, and the Broad Foundation. E. Gerard E. Mulling is conducting the trials. F. The trials are being conducted at John Hopkins University. G. 60 estimated h. Qualifications: between ages of 18 and 75, have mild or moderate CD, and be a non-smoker. I. Trial started on July 8, 2013, estimated to be completed on January 2014. 8. Vitamin D Supplementation as Non-toxic Modularization in Children With CD#8 a. Recruiting b.
Being tested is Vitamin D and if it reduces the symptoms of CD in children. C. The primary goal is to tests the children’s stool to see if the vitamin D helped reduce the symptoms of CD. D. The trial is sponsored by University of California, Los Angels, and the Broad Foundation. . David Siring, MD conducted the trial. F. The trial was conducted at the University of California. G. 20 estimated in being enrolled. H. Qualifications: aged 8 to 18 with CD. I. Trial started on January 201 0, and estimated to end on December 2013. 9. Induction of Clinical Response Using Rifleman in CD #9 a.
Recruiting b. Rifleman (placebo) is being tested on patients with CD to see if it helps with the control of diarrhea as a symptom. C. The primary goal is to test a placebo and see if it affects the diarrhea caused by CD in patients with CD. D. Scott Lee and Saliva Pharmaceuticals sponsor the trial. E. Scott D Lee, MD is conducting the trial. F. The trial is being conducted at the University of Washington. G. 40 people are estimated in being enrolled h. Qualifications: aged 18 to 80, and have CO. I. Trial started on November 2008, and estimate to end on December 2012. 10.
Efficacy and Safety Study of Terrarium Glycoside in the Treatment of CD for Induction Remission #10 a. Recruiting b. Terrarium Glycoside is being tested to see if it reduces remissions of CD. C. The primary’ goal is to assess the effect and safety of Terrarium Glycoside in the treatment of CD for induction remission and compare the hermeneutic effect with patients who received mescaline. D. The trial is sponsored by GHz Weaning. E. Wee mining GHz, PhD,MD is conducting the trial. F. The trial is being conducted at the General Surgery Institute, Jingling Hospital. G. 0 people are estimated to be enrolled. H. Qualifications: ages 18 and older, diagnosed with CD, and able to swallow tablets. I. Trial started on January 2014, and estimated to end on May 2016. IV. What are the long term consequences of CD? A. The formation of gall stones. B. The inability to absorb minerals and nutrients. 1 . Generally leaves the sufferer very Sick. C. Secondary effects include osteoporosis, arthritis, liver problems, anemia, etc. V. Case studies/ life as a victim with CD A. Roughly 700,000 Americans are diagnosed with CD 1. There is no cure to this disease as of today.
B. The pain from CD is said to be unbearable says 16 years old Carry Fisher. C. Some may experience minimal symptoms, while others desperately need surgery. VI. Costs/ time investments/ side effects/ life style changes A. According to an article on Medicals. Org, the author states that the average person with CD spends $6561 annually on medical needs associating with the eases. B. The time investment caused by CD is substantial, due to the facts patients are burdened with an inflamed GIG tract which causes them to stay near a bathroom nearly all day to relieve their symptoms.
C. Side effects of having CD include an inflamed GIG tract, abdominal pains, diarrhea, and bloating. D. There is no success rate for CD, because there is no known cure as of today. E. Life style changes that people with CD have to endure is a changing of their diet to one that is gluten free, to reduce the pressure on the GIG trace, and the abdominal pain and diarrhea that are sure to come. VII. Medical University Studies A. Universities that study CD include those in Alabama, Alaska, Arizona, Arkansas, and California. VIII.
Foundations and support groups for CD A. One of the major support groups for CD is the CAB which stands for Crown’s and Colitis Foundation of America. 1. Founded in 1967 by Irwin M. And Suzanne Rosenthal, William D. And Shelby Model, and Henry D. Janitor, M. D. 2. Non-profit organizations run by volunteers. IX. Grant money for CD A. The CAB 1. The CAB has been awarded more than 1,300 IBID grants totaling approximately SSL 64 million offending invested in research related to CD and lacerative colitis since its founding in 1967. 2.
